10 Best Oral Pain Relief Medications 2025

Looking for relief from tooth or gum pain? Look no further than our Top 10 Oral Pain Relief Medications. We scoured the market, reviewing and scoring products from a 7.2 up to an impressive 9.3, and the clear winner is Orajel 4X for Toothache & Gum Pain: Severe Cream Tube 0.33oz- from Oral Pain Relief Brand New. This powerful formula offers fast-acting relief for even the most severe pain, so you can get back to your day without distraction. And with its trusted brand name, you can trust that you're getting the best possible product on the market. Don't suffer in silence - try Orajel 4X and experience true relief.