10 Best Mattress Encasements 2025

If you're in the market for a new mattress encasement, look no further! We reviewed and scored many products in the mattress encasements category and we found products ranging from a 7.8 score up to a 9.4 score. Our top pick? The HOSPITOLOGY PRODUCTS Mattress Encasement. This zippered bed bug and dust mite proof encasement is hypoallergenic and waterproof, ensuring you'll get a good night's sleep without any unwanted visitors. Plus, the stretchable material allows it to fit mattresses with depths of 12-18 inches. Upgrade to the Sleep Defense System and protect your mattress with the best.